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Diabetic Hypoglycemia - an independent electronic journal dedicated to the advancement of hypoglycemia research and clinical management
Diabetic Hypoglycemia Volume 4, Issue 2, October 2011

News Article

News Article - electroencephalography and cognition, exercise, islet transplantation, impaired counter-regulatory response, hypoglycemia pre-conditioning, and cerebral blood flow

Emily Chu and Nicole Meinel of the Diabetic Hypoglycemia Editorial Team

Diabetic Hypoglycemia October 2011, Volume 4, Issue 2: page 22-28


Hypoglycemia as a side effect of insulin therapy is common in children with type 1 diabetes. While strict glycemic control reduces the risk of hyperglycemia-related complications, it also increases the risk of hypoglycemic episodes. Acute hypoglycemia is known to impair cognitive and motor function in adults and children with type 1 diabetes. However, the data on recurrent hypoglycemia (RH)-induced long-term cognitive impairment in children with type 1 diabetes are conflicting. Blasetti et al performed a meta-analysis of 12 studies investigating the occurrence and magnitude of cognitive impairment in children with type 1 diabetes with a history of recurrent severe hypoglycemia (SH), compared with those without SH episodes.