Diabetes Treatment Review

From self-monitoring of glucose to predictive continuous glucose monitoring

Daniella Otway and Martin Gilmour of the Diabetic Hypoglycemia Editorial Team

Diabetic Hypoglycemia June 2013, Volume 6, Issue 1: page 19-21

Abstract

The accurate measurement of blood glucose levels is essential for strict glycemic control in patients with diabetes. Continuous glucose monitoring (CGM) represents a technological advancement on the traditional method of self-monitoring blood glucose; however, this method can be associated with limited sensitivity, particularly in the hypoglycemic range, and glucose excursions are detected only once they have occurred. Predictive CGM has been developed to forecast critical glycemic deviations 30–45 minutes in advance. Clinical studies and in silico modeling suggest that predictive CGM might be an effective method for preventing/mitigating hypoglycemia and hyperglycemia events. These findings suggest that further research into predictive glucose monitoring is warranted.

Keywords: continuous glucose monitoring, glycemic control, hypoglycemia, hyperglycemia, in silico